https://github.com/alexandrovlab/sigprofilerextractor
SigProfilerExtractor allows de novo extraction of mutational signatures from data generated in a matrix format. The tool identifies the number of operative mutational signatures, their activities in each sample, and the probability for each signature to cause a specific mutation type in a cancer sample. The tool makes use of SigProfilerMatrixGenerator and SigProfilerPlotting.
bioinformatics
cancer-genomics
mutation-analysis
mutational-signatures
somatic-variants
Added: over 1 year ago - Last Synced: about 1 year ago
- Created: August 30, 2018
- Relevant topics? true
- External users? true
- Open source license? true
- Active? true
- Fork? false
- Main Language: Python
- Commits: 387
- Committers: 9
- Issues: 124
- Pull Requests: 33
- Owner: AlexandrovLab
- Stars: 146
- Forks: 51
- Packages: 4
- Downloads: 2,009
